Weight-reduction plan Capsules

Weight reduction drugs: how they work and the way efficient they’re for weight reduction

On the pharmacy counters we will discover a multitude of over-the-counter weight reduction drugs: fats burners, captagrasasas, orlistat… However do they actually work? What do it’s important to do to get the specified outcomes? We clarify it to you.

In keeping with the “European Regional Report on Weight problems 2022”, printed by the Workplace of the World Well being Group (WHO), 59% of European adults are obese or overweight and nearly all international locations have charges of over 50%.

Spain is in ninth place among the many 53 international locations analyzed, with whole charges of extra weight above 60%.

These figures give us an concept of the epidemic proportions that weight problems has reached and in addition why weight loss supplements that promise speedy weight reduction are in such excessive demand.


The sale of slimming merchandise is likely one of the hottest in pharmacies. In keeping with Dr. Diego Bellido, a doctor specializing in endocrinology and vitamin and former vice-president of the Spanish Society for the Research of Weight problems (SEEDO), spending on weight problems remedies accounts for nearly 20% of general pharmaceutical spending.

However what do specialists take into consideration over-the-counter weight loss supplements? For Bellido, there aren’t any severe medical trials to show their efficacy.

Greater than half of Spaniards are overweight or obese.

“These are subjective circumstances, which should not have any statistically important implications on the inhabitants degree,” the endocrinologist explains.

Rosa Arnau, president of the Official Faculty of Pharmacists of Castellón, maintains that “the tablet alone will hardly give the specified outcomes if it isn’t accompanied by a change in life-style”.

That is additionally basic for Dr. Bellido: “food plan with a change of habits and common train are the premise of the therapy”, he says.


The declare of sure slimming drugs and dietary supplements is that, because of them, metabolic expenditure will increase.

They sometimes comprise thermogenic chemical substances like inexperienced or crimson tea, inexperienced espresso, guarana, or caffeine.

Once more, a balanced food plan and frequent train assist elevate metabolic expenditure.

As they’re stimulant substances, it isn’t advisable to take them in the event you discover it troublesome to sleep.

As regards strictly pharmacological therapy, Bellido believes that there is no such thing as a drug that produces this thermogenic impact so far, and that is defined as a result of it will vastly enhance the center charge.
Nonetheless, “it’s a very attention-grabbing line of analysis for the longer term,” says the skilled.


Weight reduction drugs that promise to dam and seize fats are one other standard alternative. The commonest lively components in such a tablet are three:


As Rosa Arnau explains, L-carnitine is crucial for fat to enter the mitochondria, that are answerable for utilizing them as vitality (i.e. burning them).

“This chemical burns fats, however solely at excessive doses of 4 grams per day and over six months.
Then, solely intensive exercise reveals its results “Pharmacist explains.

Arnau says this element from crab shells absorbs lipids “like a sponge.”

It then carries them to the big gut to be consumed by the intestinal flora, a mechanism that may trigger fuel to kind.


It’s the lively factor of two weight problems medicine: a stronger one obtainable with a prescription and a gentler one offered with out one.

“It’s a spinoff of lipstatin, a substance that inhibits the enzyme that cuts fat (lipase) within the gut. Since they don’t seem to be minimize, they can’t be absorbed and are eradicated within the feces,” explains Rosa Arnau.

The skilled additionally tells us that it might generate unintended effects corresponding to fatty diarrhea, urgency to go to the toilet, nausea, vomiting, complications and even depressive issues.


It relies upon, above all, on the composition. “These are clearly not supposed to be taken chronically,” says the pharmacist. It’s best to comply with the producer’s directions and the recommendation of our physician or pharmacist”.

Being pregnant, nursing, diabetes, hypertension, coronary heart, and thyroid illnesses prohibit their use.

You probably have intestinal irritation or constipation, they don’t seem to be indicated.

Individuals with hypertension or thyroid issues mustn’t take them.